モーター分子Kif23の機能を損なうと、細胞分裂の乱れや細胞死が生じ、結果として大脳皮質の神経新生が悪くなって小頭症になるThis cover highlights the article Kinesin-like motor protein KIF23 maintains neural stem and progenitor cell pools in the developing cortex by Sharmin Naher, Takako Kikkawa, Noriko Osumi and colleagues. The image shows that GFP+ Kif23 knockdown cells (green) precociously differentiate into neurons and migrate to the upper area in the embryonic cortex, suggesting a function of KIF23 in the maintenance of neural stem and progenitor cells. Blue: nuclei (DAPI).
