[Important Recommendations]How can we solve both "immune disorders (allergic diseases)" and "metabolic disorders" in one fell swoop?

[Contributor's comment]:

[Keywords]:

Too much should be controlled, non-self / self-identifying ability, and artificial thymus gland to solve them all at once

[Subject]:

"How to solve both 'immune diseases' (allergic diseases) and 'metabolic disorders' at once?

[Text of the post]:

"Foxp3 gene" → "T-leg" → "reproduction and metabolism" is realized → produced by "thymus gland" →?

"T-leg" is not only controlling "self/nonself" ON/OFF, but also controlling quantitatively from 0.0 to 1.0?

Could metabolic abnormalities be "T-leg" runaway, in which the "T-leg" has lost quantitative control?

If "artificial thymus" is used to "re-educate" T-legs and "killer T cells" (i.e., strengthen their discriminatory ability).

If T-legs and killer T cells are re-educated by an artificial thymus, both immunological diseases (allergic diseases) and metabolic disorders may be solved at once.

"NR4A gene" → "Killer T cells" excessively attack "aged cells" → "Killer T" is exhausted and its attack is suppressed
→ Might it be possible to suppress the "runaway immunity (multi-organ failure, etc.)" of "Killer T"?

"Naive T" → Produced by the thymus gland, which disappears in adolescence.

Memory-type T" is generated in adulthood and after.

Create an optimized "artificial thymus" using "cell differentiation technology" such as IPS cell technology?