見出し画像

ナルコレプシー1型(脱力発作を伴うナルコレプシー)の診断の際に留意するべき除外診断項目

ナルコレプシー1型と似たような症状もしくは同一症状や検査結果(カタプレキシー、オレキシン減少)が出る可能性のある疾患一覧とその情報元リスト

List of illnessess which may cause Narcolepsy type 1 alike symptoms - cataplexy, orexin deficiency.

Somatizaion disorder 身体症状症、身体化障害、
https://www.medicalhomeportal.org/clinical-practice/common-issues-for-cyshcn/somatic-symptom-disorder-and-functional-neurologic-disorders?fbclid=IwAR0CfiZQJBKUz2X9HwP64O4O7GWCSbi-WjfJ7afJpyNdnojS0mEdK_uau1I#:~:text=Somatic%20symptom%20disorder%20(SSD)%20and,refer%20to%20different%20clinical%20presentations

Parkinson’s disease パーキンソン病
https://narcolepsy.sleep-disorders.net/parkinsons?fbclid=IwAR1VUkHNuiVVMhdNP_Vn5lIj0-vOhLGxQBpoUvcieABHKwyyN0G6ZCvmKJw&utm_source=facebook.com&utm_medium=organic

In craniopharyngiomas, 頭蓋咽頭腫 the onset of cataplectic symptoms is between 5-10 years of age, which is earlier than the peak of narcolepsy with cataplexy in children around the second decade between 12-18 years. Other conditions in which cataplexy can be seen include ischemic events 虚血性発作, multiple sclerosis 多発性硬化症, head injury 頭部傷害, paraneoplastic syndromes腫瘍随伴症候群、傍腫瘍性症候群、傍新生物性症候群 , and infections such as encephalitis 脳炎のような感染症. Cataplexy may also occur transiently or permanently due to lesions of the hypothalamus 視床下部病変 that were caused by surgery, especially in difficult tumor resections腫瘍摘出.

Several reports have documented that damage to the lateral側面 and posterior後面 hypothalamus視床下部 resulted in a loss of hypocretin producing neurons and the subsequent development of excessive daytime sleepiness and cataplexy [26, 27].

Cataplexy can be seen in infancy in association with other neurological syndromes such as Neimann-Pick type C diseaseニーマン・ピック病C型[28, 29].

http://www.scholarpedia.org/article/Cataplexy?fbclid=IwAR1lJgHGqrxfSWJEO6R1JSG7XWauB2NF2E6-Q_DFiv0lIJUlHzskFynpMks

いいなと思ったら応援しよう!