モデリングしてみます

ブレンダーのページhttps://archive.ph/aOBsW

使い方のリンク

https://x.com/hiromasafunato/status/1789520640393007522?s=46

JAMAのニュース。米国の乳牛における鳥インフルエンザ感染確認について解説している。とてもわかりやすく、この問題の重要性を示している。
とりあえず、小売のミルクからは活性を持つウイルスは検出されておらず安全。肉からも、ウイルスは検出されていない。https://t.co/2R3ttZxJFG

— 松永 和紀 (@waki1711) May 11, 2024

Study: Viral entry and translation in brain endothelia provoke influenza-associated encephalopathy

"Here we show that influenza virus enters into the cerebral endothelium and thereby induces Influenza-associated encephalopathy."

Acta Neuropathologicahttps://t.co/vp36zwADnf

— CoronaHeadsUp (@CoronaHeadsUp) May 11, 2024

CDC: Compensation for dairy worker serology tests

"We are .. making compensation available to workers in the amount of $75 for participating in that interview as well as providing a nasal swab and a blood sample for serology."

Alexander Tin’s noteshttps://t.co/3Z9TKUQ9ZZ

— CoronaHeadsUp (@CoronaHeadsUp) May 10, 2024

Preprint: Virome Sequencing Identifies H5N1 Avian Influenza in Wastewater from Nine Cities

"A variant analysis suggests avian or bovine origin but other potential sources, especially humans, could not be excluded."

medRxivhttps://t.co/2kbVMMmCJB

— CoronaHeadsUp (@CoronaHeadsUp) May 11, 2024

Author "In samples from early March onward we started finding sequencing reads that clearly derived from H5N1 influenza genomes.. in 9/10 cities we monitor"https://t.co/VCLS6DDQaA

— CoronaHeadsUp (@CoronaHeadsUp) May 11, 2024

Fresno: "Customers asking for H5N1 milk because they want immunity from it."

Founder of Fresno’s Raw Farm and the Raw Milk Institute, said his phone has been 'ringing off the hook'

Los Angeles Timeshttps://t.co/M169544A6t pic.twitter.com/vN2UWmZ4aQ

— CoronaHeadsUp (@CoronaHeadsUp) May 12, 2024

Rasmussen: “We don’t know if people can get H5N1 from drinking raw milk, .. it’s very much a possibility.”

Animals such as cats, dogs, and bears that eat dead birds have gotten diseased, and some have died from that consumption, Rasmussen said.

Agweekhttps://t.co/4cINkE8dZU

— CoronaHeadsUp (@CoronaHeadsUp) May 12, 2024

FDA: Milk pasteurization study ongoing

"The pasteurization study is ongoing and we anticipate making preliminary results available in the near future."#H5N1 https://t.co/gI4KRBAeRf pic.twitter.com/7jBvGUSyom

— CoronaHeadsUp (@CoronaHeadsUp) May 10, 2024

Fresno: "Customers asking for H5N1 milk because they want immunity from it."

Founder of Fresno’s Raw Farm and the Raw Milk Institute, said his phone has been 'ringing off the hook'

Los Angeles Timeshttps://t.co/M169544A6t pic.twitter.com/vN2UWmZ4aQ

— CoronaHeadsUp (@CoronaHeadsUp) May 12, 2024

Michigan: Five more dairy herds infected with HPAI

HPAI confirmed in "Allegan, Clinton, Gratiot, Ingham counties and an additional herd in Isabella"#H5N1 pic.twitter.com/NkMiZBH4XX

— CoronaHeadsUp (@CoronaHeadsUp) May 10, 2024

US: Indemnification program for dairy farms to be based on the amount of milk lost from cows with H5N1 https://t.co/WFlmxkQJny

— CoronaHeadsUp (@CoronaHeadsUp) May 10, 2024

UK: H5N1

“Very Low” is defined as “Very rare but cannot be excluded”.

The probability is not Negligible because although highly likely, it is not certain that dried milk powder imported from the US has undergone sufficient processing to eliminate any infectious virus present.

— CoronaHeadsUp (@CoronaHeadsUp) May 10, 2024

H5N1: Vaccine shots for cattle https://t.co/FD00qtF04a

— CoronaHeadsUp (@CoronaHeadsUp) May 9, 2024

USDA bars poultry imports from France due to avian flu vaccination issues

CIDRAP, October 2023https://t.co/wQhlaATbKt

— CoronaHeadsUp (@CoronaHeadsUp) May 9, 2024

.@USDA reports 6 new herds that have tested positive for #H5N1 #birdflu today, the first new confirmations since 4/25.
No new states reporting. Four new herds in Michigan and one apiece in Idaho and Colorado.
National total of confirmed herds: 42.https://t.co/6E4b6hAXBu pic.twitter.com/cR7iBh5p67

— Helen Branswell 🇨🇦 (@HelenBranswell) May 9, 2024

CNN: High concentrations of H5N1 virus found in milk

"the concentration of H5N1 viruses in the milk of infected cows is 1,000 times higher than typically seen in infected birds."

CNNhttps://t.co/6O5NZKPvns

— CoronaHeadsUp (@CoronaHeadsUp) May 10, 2024

FDA chief says feds are preparing for low probability of bird flu moving to humans

“This virus, like all viruses, is mutating. We need to continue to prepare for the possibility that it might jump to humans.”

Iowa Capital Dispatchhttps://t.co/E3VpcdzheR

— CoronaHeadsUp (@CoronaHeadsUp) May 8, 2024

H5N1: Vaccine shots for cattle https://t.co/FD00qtF04a

— CoronaHeadsUp (@CoronaHeadsUp) May 9, 2024

"If H5N1 becomes pandemic, we are currently in chapter 1

To prevent a chapter 2, the most important tool in our arsenal is widespread surveillance testing"

Testing is how we see the virus – Lets not fly blind

Myself & @JanikaSchmitt write for @TIME https://t.co/xSr0nX2tCz

— Michael Mina (@michaelmina_lab) May 9, 2024

USDA bars poultry imports from France due to avian flu vaccination issues

CIDRAP, October 2023https://t.co/wQhlaATbKt

— CoronaHeadsUp (@CoronaHeadsUp) May 9, 2024

Michigan: HPAI in a dairy herd and a backyard flock from Ionia County.

Fresh detections of highly pathogenic avian influenza (HPAI) in both a dairy herd and a backyard flock from Ionia County announced on 9th May 2024.#H5N1 pic.twitter.com/UwuL146QqZ

— CoronaHeadsUp (@CoronaHeadsUp) May 9, 2024

H5N1 in cattle: APHIS not updating online records

Neither the above report of HPAI in cattle in Michigan, nor another confirmed report from them on 6th May 2024, have been added to the APHIS web page athttps://t.co/HEe4fqoJO3 pic.twitter.com/BHPOIrDFgw

— CoronaHeadsUp (@CoronaHeadsUp) May 9, 2024

APHIS updates its online recordshttps://t.co/HEe4fqoJO3 pic.twitter.com/YIT6La6yK1

— CoronaHeadsUp (@CoronaHeadsUp) May 9, 2024

Fifth herd of dairy cows in Michigan contracts bird flu

"The herd is located in Ionia County, which had one previous herd diagnosed with the disease this year."https://t.co/PXdcghoBAr

— CoronaHeadsUp (@CoronaHeadsUp) May 9, 2024

FDA: The mortality rate of cows with [H5N1] is less than 1%

Dr. Robert Califf, FDA, livestream from 30 minutes in:https://t.co/HA9zmzLjmb pic.twitter.com/Pi9iLdhr5Q

— CoronaHeadsUp (@CoronaHeadsUp) May 9, 2024

The more virus allowed to enter the food supply & be shipped to processors, the more typical pasteurization is going to struggle to kill it all.

There must be tests & controls placed on how much infected milk is allowed to leave the farm.

There must also be tests to adjust… https://t.co/o1LswswHD3

— Rick Bright (@RickABright) May 8, 2024

FDA chief says feds are preparing for low probability of bird flu moving to humans

“This virus, like all viruses, is mutating. We need to continue to prepare for the possibility that it might jump to humans.”

Iowa Capital Dispatchhttps://t.co/E3VpcdzheR

— CoronaHeadsUp (@CoronaHeadsUp) May 8, 2024

.@USDA reports 6 new herds that have tested positive for #H5N1 #birdflu today, the first new confirmations since 4/25.
No new states reporting. Four new herds in Michigan and one apiece in Idaho and Colorado.
National total of confirmed herds: 42.https://t.co/6E4b6hAXBu pic.twitter.com/cR7iBh5p67

— Helen Branswell 🇨🇦 (@HelenBranswell) May 9, 2024

.@HelenBranswell, thanks for update. I don’t see the new herds on the table you linked. Also don’t see any new virus sequences shared since May 2, largely from viruses collected mid-March to 1st week of April. Have you found any recent data to help track the virus evolution?

— Rick Bright (@RickABright) May 9, 2024

These are the new outbreaks, @RickABright.
I haven't been looking for new sequence data. I depend on people far smarter than me to find/mine it. @PeacockFlu @MichaelWorobey @evogytis? pic.twitter.com/93L6XwZtQw

— Helen Branswell 🇨🇦 (@HelenBranswell) May 9, 2024

そういうことですね。
てか、同じようなこと、宮沢先生なんかの講演会でアンチがやってましたよね。
会場や主催者、大学にも電凸して中止に追い込んで喜んでましたもんね。 https://t.co/DcCVyNwqLt

— yoshi h (@BNandRainbow) May 1, 2024

The spread of the #H5N1 avian #influenza virus („bird flu“) in cows in the USA is very unusual and worrisome. Martin Beer @Loeffler_News heads one of the very few BSL-3 labs permitting the study of viruses in such large animals. Very interesting article in @ScienceMagazine ⬇️ https://t.co/NkX8qNtQU2

— GfV - Gesellschaft für Virologie (@GesVirologie) May 8, 2024

After 10 months off for my science journalism fellowship at MIT I’m jumping back into infectious disease reporting and uh boy I’m not gonna be bored am I?!

Here's a first story on #h5n1 in cows (and I'll try to write a thread later):https://t.co/Q3oN6qSssS

— Kai Kupferschmidt (@kakape) May 7, 2024

3/ While changes in HA binding are only one of many required, they are thought to be key in governing influenza host range. https://t.co/cwM6mlGexw

— Sam Scarpino (@svscarpino) May 6, 2024

3/ While changes in HA binding are only one of many required, they are thought to be key in governing influenza host range. https://t.co/cwM6mlGexw

— Sam Scarpino (@svscarpino) May 6, 2024

4/ So why are pigs called an "evolutionary lab for flu host switching" and why I am worried about the latest news about cow mammary glands?

Pigs express both the human-flu and avian-flu host cell receptors in their upper-respiratory tract. https://t.co/l53O7OBiTv pic.twitter.com/UmRJriNmbr

— Sam Scarpino (@svscarpino) May 6, 2024

5/ As a result, influenza may evolve changes in host cell binding preference w/in pigs and pigs can potentially become infected with both human & avian flus.

When this kind of "super infection" occurs, viruses can undergo re-assortment where segments of their genome are swapped.

— Sam Scarpino (@svscarpino) May 6, 2024

6/ Both the presence of the two cell receptor types and potential for reassortment between human and avian flu is why scientists often refer to pigs as "evolutionary labs for flu host switching." https://t.co/5YIS5eDaZC

— Sam Scarpino (@svscarpino) May 6, 2024

Science Mag article: “It’s incredibly difficult to get the right sample sets off the infected farms. It’s clearly a barrier to understanding what’s going on. … That’s why these experimental infections of cows are really going to be super informative.”

— CoronaHeadsUp (@CoronaHeadsUp) May 7, 2024

H5N1: Avian flu in cattle in Barry County, MIchigan

"Michigan Department of Agriculture and Rural Development (MDARD) Director Tim Boring announced the detection of highly pathogenic avian influenza (HPAI) in a dairy herd from Barry County."

Date: 6th May 2024 pic.twitter.com/VubGh7Fout

— CoronaHeadsUp (@CoronaHeadsUp) May 7, 2024

1/ New #H5N1 pre-print ⬆️ the threat level for the ongoing outbreak in dairy cows.

Researchers found that cow mammary glands contain the same kind of mixed flu receptors seen in pigs.

This mix of receptors is why scientists call pigs "evolutionary labs for flu host switching". pic.twitter.com/N1dBKEn2W0

— Sam Scarpino (@svscarpino) May 6, 2024

2/ One of the key changes required for avian flu to transmit effectively in humans involves flu's hemagglutinin (HA) host cell receptor preference.

tl;dr The cell surface receptor influenza uses in birds is subtly different from the one in the human upper-respiratory tract. pic.twitter.com/bS1uk7slNj

— Sam Scarpino (@svscarpino) May 6, 2024

Politico: Covid lessons remain unlearned as avian flu infects cattle, hospitals say

"The politics are, if anything, further against public health than they were before the [Covid] pandemic.”

POLITICOhttps://t.co/bEdtc0YWPV

— CoronaHeadsUp (@CoronaHeadsUp) May 7, 2024

BREAKING: New unclassified State Department documents have confirmed that COVID-19 leaked from a lab in Wuhan, China, and the Chinese Communist Party (CCP) attempted to cover it up. pic.twitter.com/KQNbmYSQMX

— The General (@GeneralMCNews) May 7, 2024

https://archive.ph/JFbsQ

https://archive.ph/JFbsQ

https://x.com/flybasedotorg/status/1782882081200365869?s=46

https://x.com/dataeiyosusume/status/1783100828280402302?s=46

じつは、「麹菌」は日本にしかいなかった…欧米も認めたその安全性の真実とは(現代ビジネス)#Yahooニュースhttps://t.co/Mq1cDL9JoA

— 🔰🍶DRY🍶🔰 (@daruya2) April 24, 2024

https://x.com/nikkeibiotech/status/1783284929885049297?s=46

https://x.com/anna2023043041/status/1783013094727520279?s=46

https://x.com/coconeicicle/status/1783416705043357847?s=46

【本日17時まで！】「自閉症・ADHD・学習障害等に関わる染色体欠失疾患の改善に貢献したい。」要因となる22番染色体の部分欠損の中でもなかでも、ゲノムDNAを安全に保つDGCR8機能に着目し、神経精神症状の改善を目指します。 #academist https://t.co/NAQ0FMyidH

— academist (@academist_cf) April 25, 2024

武漢の決定打：🇩🇪・🇨🇳研究所とHIV挿入https://t.co/9puyfk4fb9
HIV-1 gp120挿入論文https://t.co/qIkEOLsAXe
2020/4Montagnier
コロナが生鮮市場出現説を却下
HIV挿入→HIV💉研究？人工説の可能性が高いと主張https://t.co/VXy4yYGqpL https://t.co/iDBiwBIPtl pic.twitter.com/rnyi4TpSmf

— tune (@keisuke4713) April 26, 2024

100年前の酵母を現代へ。

▼目覚めよ、アカツキ #note https://t.co/QJdJAvV84v

— ヒライユウキ｜日詰平井邸 (@HIRA6kiku) April 28, 2024

H5N1: Reduced susceptibility to neuraminidase inhibitors

"CDC found one virus from a cow with a marker known to be associated with reduced susceptibility to the neuraminidase inhibitors (a change at NA-T438I)."

CDC #H5N1 updatehttps://t.co/FO7YAZsAcw

— CoronaHeadsUp (@CoronaHeadsUp) April 27, 2024

Gut microbiome and metabolome profiling in Framingham heart study reveals cholesterol-metabolizing bacteria
コレステロールを代謝する腸内細菌をメタボロミクスを含むコホート統合解析で発見。フラボノイドについての結果も興味深い。#JustDoMetabolomics https://t.co/okIURCKu9Y

— Ryo Nakabayashi (@Digging_Plants) April 27, 2024